William J Jusko Selected Research

birinapant

10/2018	Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts.
1/2018	Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells.
1/2018	Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells.
10/2015	Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

William J Jusko Research Topics

Disease

19	Disease Progression 01/2019 - 01/2008
17	Rheumatoid Arthritis 05/2020 - 08/2008
12	Neoplasms (Cancer) 10/2019 - 05/2009
11	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2013
10	Body Weight (Weight, Body) 06/2021 - 02/2002
10	Inflammation (Inflammations) 01/2017 - 02/2011
9	Edema (Dropsy) 01/2017 - 08/2008
8	Experimental Arthritis 01/2017 - 08/2008
7	Insulin Resistance 10/2018 - 01/2005
6	Arthritis (Polyarthritis) 10/2018 - 08/2008
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020 - 05/2002
4	Type 2 Diabetes Mellitus (MODY) 01/2014 - 02/2011
3	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 10/2020 - 10/2018
3	Obesity 06/2020 - 01/2017
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2013 - 05/2010
3	Hyperinsulinism (Hyperinsulinemia) 06/2011 - 01/2009
2	Cerebral Palsy (Spastic Diplegia) 01/2018 - 05/2014
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2018 - 05/2010
2	Endotoxemia 01/2017 - 03/2005
2	Adenocarcinoma 09/2013 - 05/2013
2	Weight Gain 06/2012 - 12/2011
2	Chronic Disease (Chronic Diseases) 01/2012 - 06/2011
1	Autoimmune Hepatitis 01/2022
1	Brain Injuries (Brain Injury) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Bone Resorption 10/2018
1	Crohn Disease (Crohn's Disease) 10/2018
1	Muscle Spasticity (Spastic) 01/2018
1	Pain (Aches) 01/2017

Drug/Important Bio-Agent (IBA)

20	Pharmaceutical PreparationsIBA 10/2020 - 08/2002
11	Glucose (Dextrose)FDA LinkGeneric 01/2013 - 01/2005
10	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019 - 05/2002
10	CollagenIBA 09/2018 - 08/2008
9	Gemcitabine FDA Link 01/2021 - 09/2013
9	Insulin (Novolin)FDA Link 01/2013 - 01/2005
8	Methylprednisolone FDA LinkGeneric 01/2019 - 11/2003
7	Dexamethasone (Maxidex)FDA LinkGeneric 05/2020 - 11/2003
6	Messenger RNA (mRNA)IBA 01/2014 - 04/2008
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2015
5	CytokinesIBA 01/2017 - 05/2002
5	Prednisolone (Predate)FDA LinkGeneric 03/2005 - 05/2002
4	Biomarkers (Surrogate Marker)IBA 10/2018 - 06/2011
4	birinapantIBA 10/2018 - 10/2015
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 08/2002
4	Interleukin-6 (Interleukin 6)IBA 01/2016 - 08/2008
3	VBP15 compoundIBA 10/2020 - 10/2018
3	GlucocorticoidsIBA 10/2018 - 01/2005
3	Etanercept (Enbrel)FDA Link 10/2018 - 07/2011
3	InterleukinsIBA 01/2018 - 08/2008
3	Monoclonal AntibodiesIBA 01/2018 - 05/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 08/2008
3	salicylsalicylic acid (salsalate)IBA 01/2014 - 12/2011
3	Everolimus FDA Link 05/2013 - 01/2013
3	Sorafenib (BAY 43-9006)FDA Link 05/2013 - 01/2013
3	CorticosteroneIBA 08/2008 - 07/2008
2	SteroidsIBA 06/2020 - 02/2002
2	Contraceptive Agents (Contraceptives)IBA 06/2020 - 01/2017
2	tofacitinibIBA 05/2020 - 01/2019
2	Baclofen FDA LinkGeneric 01/2018 - 05/2014
2	Inhibitor of Apoptosis ProteinsIBA 01/2018 - 10/2015
2	Naproxen (Naprosyn)FDA LinkGeneric 01/2017 - 01/2017
2	Blood Proteins (Serum Proteins)IBA 01/2017 - 06/2003
2	TrabectedinIBA 01/2016 - 01/2016
2	Immunosuppressive Agents (Immunosuppressants)IBA 05/2013 - 09/2004
2	Phosphotransferases (Kinase)IBA 05/2013 - 01/2013
2	TOR Serine-Threonine KinasesIBA 05/2013 - 01/2013
2	otelixizumabIBA 11/2010 - 05/2010
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 09/2010 - 04/2007
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 08/2008 - 08/2008
2	Therapeutic UsesIBA 06/2008 - 06/2003
2	Interleukin-10 (Interleukin 10)IBA 03/2005 - 05/2002
1	Phosphodiesterase InhibitorsIBA 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 06/2021
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2021
1	Hormones (Hormone)IBA 06/2020
1	inter-alpha-inhibitorIBA 01/2020
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2020
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 10/2019
1	Liposomes (Liposome)IBA 10/2019
1	Combined Oral ContraceptivesIBA 01/2019
1	DystrophinIBA 01/2019
1	Janus KinasesIBA 01/2019
1	Janus Kinase InhibitorsIBA 01/2019
1	Drug CombinationsIBA 01/2018
1	Trifluoperazine (Stelazine)FDA LinkGeneric 01/2018
1	Interleukin-12 (IL 12)IBA 01/2018
1	Interleukin-17 (Interleukin 17)IBA 01/2018
1	Ustekinumab (CNTO 1275)FDA Link 01/2018
1	Interleukin-23 (Interleukin 23)IBA 01/2018
1	AlbuminsIBA 01/2017
1	Ethinyl Estradiol (Estinyl)FDA LinkGeneric 01/2017
1	Progestins (Progestagens)IBA 01/2017
1	MitogensIBA 01/2017

Therapy/Procedure

7	Therapeutics 03/2016 - 09/2004
2	Hemodilution 06/2012 - 12/2008
2	Drug Therapy (Chemotherapy) 06/2008 - 05/2002
1	Postcoital Contraception (Emergency Contraception) 06/2020
1	Hormonal Contraception 06/2020
1	Lasers (Laser) 10/2019
1	Resuscitation 01/2017